Akihisa Ikeno

Discovery and Preclinical Characterization of (+)-3-[4-(1- Piperidinoethoxy)phenyl]spiro[indene- 1,1‘-indane]-5,5‘-diol Hydrochloride:  A Promising Nonsteroidal Estrogen Receptor Agonist for Hot Flush

Nobuhide Watanabe, Akihisa Ikeno, Hisao Minato et al. · Journal of Medicinal Chemistry · 2003 · 36 citations · Full text

Hormonal Contraceptive, Gynecology, Pharmacotherapy +16

4-(4-Alkylpiperazin-1-yl)phenyl group: A novel class of basic side chains for selective estrogen receptor modulators

Nobuhide Watanabe, Hiroshi Nakagawa, Akihisa Ikeno et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 28 citations

Medicinal Chemistry, Biochemistry, Functional Selectivity +11

Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors

Kentaro Takai, Naoki Chiyo, Tomoko Nakajima et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 18 citations · Full text

Medicinal Chemistry, Aldo-keto Reductase, Biochemistry +9

Antihypertensive Effects of AJ-2615, a New Calcium Antagonist with α1-Adrenergic Blocking Activity in Experimental Hypertensive Animals

Akihisa Ikeno, Isamu Nose, Fumiyo Fukuya et al. · Journal of Cardiovascular Pharmacology · 1993 · 10 citations

Antihypertensive mechanism of alacepril: effect on norepinephrine-induced vasoconstrictive response in vitro and in vivo.

K Takeyama, Hiroshi Minato, Akihisa Ikeno et al. · PubMed · 1986 · 10 citations

Peripheral Vascular Bed, Molecular Pharmacology, Hypertension +13