Karen Oldman

A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions

Lorna Ewart, Aileen Milne, Debbie Adkins et al. · Journal of Pharmacological and Toxicological Methods · 2013 · 50 citations

Drug Safety, B Regulatory Submissions, Preclinical Drug Evaluation +7

Enhanced Characterization of Contractility in Cardiomyocytes During Early Drug Safety Assessment

Larissa Butler, Caroline Cros, Karen Oldman et al. · Toxicological Sciences · 2015 · 41 citations · Full text

Assessment of extracellular field potential and Ca2+ transient signals for early QT/pro-arrhythmia detection using human induced pluripotent stem cell-derived cardiomyocytes

Najah Abi‐Gerges, Amy Pointon, Karen Oldman et al. · Journal of Pharmacological and Toxicological Methods · 2016 · 33 citations

Ca2+ Transient Signals, Cardiomyopathy, Heart Failure +10

Preservation of cardiomyocytes from the adult heart

Najah Abi‐Gerges, Amy Pointon, Georgia F. Pullen et al. · Journal of Molecular and Cellular Cardiology · 2013 · 27 citations

Cardiac Muscle, Cardiomyopathy, Heart Failure +8

The rat bone marrow micronucleus test--study design and statistical power

Julie E. Hayes, Ann Doherty, D. J. Adkins et al. · Mutagenesis · 2009 · 26 citations

Blood Cell, Biomedical Engineering, Statistical Power +19