Naoki Aikawa

Effect of Eritoran, an Antagonist of MD2-TLR4, on Mortality in Patients With Severe Sepsis

Steven M. Opal, Pierre‐François Laterre, Bruno François et al. · JAMA · 2013 · 795 citations · Full text

Veterinary Medicine, Pharmacology, Pharmacotherapy +11

Efficacy and safety of recombinant human soluble thrombomodulin (ART‐123) in disseminated intravascular coagulation: results of a phase III, randomized, double‐blind clinical trial

Hiroaki Saito, Ikuro Maruyama, S Shimazaki et al. · Journal of Thrombosis and Haemostasis · 2006 · 600 citations

Medicine, Hematology, Pharmacology +11

Sarin poisoning in Tokyo subway

Toru Suzuki, Hiroyuki Morita, Kazuyuki Ono et al. · The Lancet · 1995 · 356 citations

Pharmacy, Clinical Toxicology, Toxicology +6

A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation*

Jean‐Louis Vincent, M Ramesh, David Ernest et al. · Critical Care Medicine · 2013 · 322 citations

Medicine, Pharmacology, Pharmacotherapy +15

Neutrophil-Derived Matrix Metalloproteinase 9 Triggers Acute Aortic Dissection

Tomohiro Kurihara, Ryoko Shimizu‐Hirota, Masayuki Shimoda et al. · Circulation · 2012 · 258 citations

Veterinary Medicine, Cardiology, Pathobiology +11