Chang Huang

Inhibition of phosphodiesterase 4 by FCPR16 protects SH-SY5Y cells against MPP+-induced decline of mitochondrial membrane potential and oxidative stress

Jiahong Zhong, Hui Yu, Chang Huang et al. · Redox Biology · 2018 · 75 citations · Full text

Medicine, Neuroscience, Pharmacology +17

miR‐215‐5p is an anticancer gene in multiple myeloma by targeting RUNX1 and deactivating the PI3K/AKT/mTOR pathway

Shuyan Liu, Yun Zhang, Chang Huang et al. · Journal of Cellular Biochemistry · 2019 · 54 citations

Life Sciences, Molecular Medicine, Oncology +16

FCPR16, a novel phosphodiesterase 4 inhibitor, produces an antidepressant-like effect in mice exposed to chronic unpredictable mild stress

Qiuping Zhong, Hui Yu, Chang Huang et al. · Progress in Neuro-Psychopharmacology and Biological Psychiatry · 2018 · 40 citations

Medicine, Neuroscience, Pharmacology +16

Development of highly potent phosphodiesterase 4 inhibitors with anti-neuroinflammation potential: Design, synthesis, and structure-activity relationship study of catecholamides bearing aromatic rings

Zhong‐Zhen Zhou, Bing-Chen Ge, Qiuping Zhong et al. · European Journal of Medicinal Chemistry · 2016 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Genetic aberration in primary hepatocellular carcinoma: correlation between p53 gene mutation and loss-of-hetero- zygosity on chromosome 16q21-q23 and 9p21-p23

Gang Greg Wang, Chang Huang, Yan Zhao et al. · Cell Research · 2000 · 35 citations

Medicine, Genetics, Molecular Genetics +16