Igor José dos Santos Nascimento

The New Era of Drug Discovery: The Power of Computer-aided DrugDesign (CADD)

Igor José dos Santos Nascimento, Thiago Mendonça de Aquino, Edeildo Ferreira da Silva‐Júnior · Letters in Drug Design & Discovery · 2022 · 104 citations

Computer-aided design of 1,4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases

Leandro Rocha Silva, Ari Souza Guimarães, Jadiely do Nascimento et al. · Bioorganic & Medicinal Chemistry · 2021 · 57 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +11

Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors

Igor José dos Santos Nascimento, Paulo Fernando da Silva Santos-Júnior, Thiago Mendonça de Aquino et al. · European Journal of Medicinal Chemistry · 2021 · 40 citations · Full text

Viral Replication, Molecular Virology, Pathogenesis +6

Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes

Thiago Mendonça de Aquino, Paulo Henrique Barcellos França, Érica E. E. S. Rodrigues et al. · Medicinal Chemistry · 2021 · 27 citations · Full text

Dynamic Cross-Correlation Matrix (DCCM) Reveals New Insights to Discover New NLRP3 Inhibitors Useful as Anti-Inflammatory Drugs

Igor José dos Santos Nascimento, Marianny de Souza, Daniel Calazans Medeiros et al. · ECMC 2022 · 2022 · 27 citations · Full text