HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment

Leona Matsumoto, Yasushi Hirota, Tomoko Saito‐Fujita, +12

Journal of Clinical Investigation

FertilityGynecologyFemale Reproductive SystemFemale Reproductive FunctionReproductive Biology +20

F4/80+ Macrophages Contribute to Clearance of Senescent Cells in the Mouse Postpartum Uterus

Mahiro Egashira, Yasushi Hirota, Ryoko Shimizu‐Hirota, +12

Endocrinology

ImmunologyGynecologyCell DeathCellular PhysiologyEmbryology +16

Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion

Shun Akaeda, Yasushi Hirota, Yamato Fukui, +12

EMBO Reports

Developmental BiologyCell DivisionEmbryo InvasionImplantation (Embryology)Retinoblastoma Protein +7

STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation

Takehiro Hiraoka, Yasushi Hirota, Tomoko Saito‐Fujita, +8

JCI Insight

CD206+ M2-Like Macrophages Are Essential for Successful Implantation

Yosuke Ono, Osamu Yoshino, Takehiro Hiraoka, +10

Frontiers in Immunology

MicroRNA-200a Locally Attenuates Progesterone Signaling in the Cervix, Preventing Embryo Implantation

Hirofumi Haraguchi, Tomoko Saito‐Fujita, Yasushi Hirota, +12

Molecular Endocrinology

FertilityReproductive HealthGynecologyCell ProliferationFemale Reproductive System +25

Mdm2‐p53‐SF1 pathway in ovarian granulosa cells directs ovulation and fertilization by conditioning oocyte quality

Hirofumi Haraguchi, Yasushi Hirota, Tomoko Saito‐Fujita, +12

The FASEB Journal

OocyteFertilityMdm2‐p53‐sf1 PathwayGynecologyFemale Reproductive System +19

Differential roles of uterine epithelial and stromal STAT3 coordinate uterine receptivity and embryo attachment

Takehiro Hiraoka, Yasushi Hirota, Yamato Fukui, +13

Scientific Reports

IL-33 Exacerbates Endometriotic Lesions via Polarizing Peritoneal Macrophages to M2 Subtype

Yosuke Ono, Osamu Yoshino, Takehiro Hiraoka, +9

Reproductive Sciences

InflammationCytokineAutoimmune DiseaseImmunologyPolarizing Peritoneal Macrophages +9

CD206+ macrophage is an accelerator of endometriotic-like lesion via promoting angiogenesis in the endometriosis mouse model

Yosuke Ono, Osamu Yoshino, Takehiro Hiraoka, +11

Scientific Reports