Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

Marina Lesina, Magdalena U. Kurkowski, Katharina Ludes, +9

Cancer Cell

Signaling PathwayPancreatic CancerMedicineImmunologyPathology +6

IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality

Hong Zhang, Patrick Neuhöfer, Liang Song, +15

Journal of Clinical Investigation

A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis

Heiko Witt, Miklós Sahin‐Tóth, Olfert Landt, +60

Nature Genetics

Pancreatic CancerPancreatic Fluid CollectionImmunologyGastroenterologyPathology +3

<i>CFTR</i>, <i>SPINK1</i>, <i>CTRC</i> and <i>PRSS1</i> variants in chronic pancreatitis: is the role of mutated <i>CFTR</i> overestimated?

Jonas Rosendahl, Olfert Landt, Jana Bernadova, +14

Gut

Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis

Hana Algül, Matthias Treiber, Marina Lesina, +6

Journal of Clinical Investigation

Inflammatory Lung DiseaseImmunologyPathologyCell DeathInflammation +16

Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship

Kathrin Rothe, Susanne Feihl, Jochen Schneider, +14

European Journal of Clinical Microbiology & Infectious Diseases

Myeloid, but Not Pancreatic, RelA/p65 Is Required for Fibrosis in a Mouse Model of Chronic Pancreatitis

Matthias Treiber, Patrick Neuhöfer, E Anetsberger, +8

Gastroenterology

InflammationFibrosisChronic PancreatitisPancreatic Fluid CollectionImmunology +6

Intensive Care Risk Estimation in COVID-19 Pneumonia Based on Clinical and Imaging Parameters: Experiences from the Munich Cohort

Egon Burian, Friederike Jungmann, Georgios Kaissis, +13

Journal of Clinical Medicine

Advanced Lung DiseaseCovid-19 EpidemiologyCovid-19Intensive Care UnitClinical Epidemiology +17

Deletion of IκBα Activates RelA to Reduce Acute Pancreatitis in Mice Through Up-regulation of Spi2A

Patrick Neuhöfer, Liang Song, Henrik Einwächter, +13

Gastroenterology

InflammationCytokineMolecular PhysiologyMucosal ImmunologyImmune Regulation +10

Prediction of extubation failure in medical intensive care unit patients

Bernd Saugel, Philipp Rakette, Alexander Hapfelmeier, +10

Journal of Critical Care

Critical Care ManagementAcute CarePatient SafetyDiagnosisSepsis +5