Ellen Y. Cotrina

Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease

Ellen Y. Cotrina, Luís Miguel Santos, Josep Rivas et al. · European Journal of Medicinal Chemistry · 2021 · 30 citations · Full text

Drug Discovery Program, Drug Target, Neurochemical Biomarkers +20

Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal

Ana Gimeno, Luís Miguel Santos, Mobina Alemi et al. · Journal of Medicinal Chemistry · 2017 · 29 citations · Full text

Modulation of the Fibrillogenesis Inhibition Properties of Two Transthyretin Ligands by Halogenation

Ellen Y. Cotrina, Marta Pinto, Lluís Bosch et al. · Journal of Medicinal Chemistry · 2013 · 27 citations

Protein Assembly, Halogenation Strategies, Molecular Biology +20

Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD

Xabier Ríos, Vanessa Gómez‐Vallejo, Abraham Martín et al. · Scientific Reports · 2019 · 26 citations · Full text

Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer’s Disease Drug Discovery

Ellen Y. Cotrina, Ana Gimeno, Jordi Llop et al. · Journal of Medicinal Chemistry · 2020 · 26 citations · Full text