Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen

Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, +29

ACS Pharmacology & Translational Science

Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities

Angela Corona, Krzysztof Wycisk, Carmine Talarico, +11

ACS Pharmacology & Translational Science

Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor

Delia Tarantino, Rolando Cannalire, Eloise Mastrangelo, +7

Antiviral Research

Chemical BiologyViral ReplicationBiochemistryNatural SciencesMolecular Biology +13

2-Phenylquinoline <i>S. aureus</i> NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction

Tommaso Felicetti, Rolando Cannalire, Donatella Pietrella, +11

Journal of Medicinal Chemistry

Pharmaceutical SciencePharmacotherapyAntimicrobial ChemotherapyPharmaceutical ChemistryDrug Resistance +17

The Versatile Nature of the 6-Aminoquinolone Scaffold: Identification of Submicromolar Hepatitis C Virus NS5B Inhibitors

Giuseppe Manfroni, Rolando Cannalire, Maria Letizia Barreca, +13

Journal of Medicinal Chemistry

Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase

Rolando Cannalire, Kitti Wing Ki Chan, Maria Sole Burali, +11

ACS Medicinal Chemistry Letters

Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium

Rolando Cannalire, Diana Machado, Tommaso Felicetti, +9

European Journal of Medicinal Chemistry

Inhibitory ActivityMedicinal ChemistryAntifungal AgentMedicineMycobacterium Avium +8

Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against <i>Escherichia coli</i>

Diana Machado, Laura Fernandes, Sofia Santos Costa, +6

PeerJ

New Pyrazolobenzothiazine Derivatives as Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors

Giuseppe Manfroni, Dinesh Manvar, Maria Letizia Barreca, +13

Journal of Medicinal Chemistry

Antiviral DrugPharmaceutical ChemistryDrug ResistanceMolecular PharmacologyMedicinal Chemistry +17

Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase

Rolando Cannalire, Delia Tarantino, Andrea Astolfi, +9

European Journal of Medicinal Chemistry

2,1-Benzothiazine 2,2-DioxidesBiochemistryNatural SciencesRna Structure PredictionAntiviral Drug Development +6