David Mikeladze

Sigma-1 Receptor Agonists Induce Oxidative Stress in Mitochondria and Enhance Complex I Activity in Physiological Condition but Protect Against Pathological Oxidative Stress

Nino Goguadze, Elene Zhuravliova, Didier Morin et al. · Neurotoxicity Research · 2017 · 98 citations

Life Sciences, Biochemistry, Pharmacology +15

Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria

Nino Natsvlishvili, Nino Goguadze, Elene Zhuravliova et al. · BMC Biochemistry · 2015 · 68 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

TNF-<i>α</i> Downregulation Modifies Insulin Receptor Substrate 1 (IRS-1) in Metabolic Signaling of Diabetic Insulin-Resistant Hepatocytes

Iraj Alipourfard, Nelly Datukishvili, David Mikeladze · Mediators of Inflammation · 2019 · 67 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity

Elene Zhuravliova, Tamar Barbakadze, Nino Natsvlishvili et al. · Neurochemistry International · 2006 · 40 citations

Pharmacy, Neuroscience, Pharmacology +16

Creatine enhances survival of glutamate‐treated neuronal/glial cells, modulates Ras/NF‐κB signaling, and increases the generation of reactive oxygen species

Elena Juravleva, Tamar Barbakadze, David Mikeladze et al. · Journal of Neuroscience Research · 2004 · 40 citations

Life Sciences, Neurobiology, Neuroscience +17