Deficient expression of NCR in NK cells from acute myeloid leukemia: evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction

Cyril Fauriat, Sylvaine Just‐Landi, Françoise Mallet, +4

Blood

Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities.

Régis Costello, Françoise Mallet, Béatrice Gaugler, +4

PubMed

Hematological MalignancyTumor BiologyFas-induced ApoptosisMixed-phenotype Acute LeukemiaImmunology +13

Regulation of CD80/B7-1 and CD86/B7-2 molecule expression in human primary acute myeloid leukemia and their role in allogenic immune recognition

Régis Costello, Françoise Mallet, Danielle Sainty, +3

European Journal of Immunology

LIGHT costimulates CD40 triggering and induces immunoglobulin secretion; a novel key partner in T cell‐dependent B cell terminal differentiation

Thomas Duhen, Christine L. Pasero, Françoise Mallet, +3

European Journal of Immunology

Lymphocyte DevelopmentAdaptive Immune SystemImmunologyPathologyImmunologic Mechanism +18

NKG2C⁺ memory‐like NK cells contribute to the control of HIV viremia during primary infection: Optiprim‐ANRS 147

Françoise Gondois‐Rey, Antoine Chéret, Samuel Granjeaud, +12

Clinical & Translational Immunology

The immunophenotype of minimally differentiated acute myeloid leukemia (AML-M0): reduced immunogenicity and high frequency of CD34+/CD38− leukemic progenitors

Françoise Mallet, Hérvè Chambost, D Sainty, +3

Leukemia

Hematological MalignancyImmune Cell DevelopmentAcute Myeloid LeukemiaImmunologyHematology +6

Primary B-CLL Resistance to NK Cell Cytotoxicity can be Overcome In Vitro and In Vivo by Priming NK Cells and Monoclonal Antibody Therapy

Caroline Veuillen, Thérèse Aurran‐Schleinitz, Rémy Castellano, +12

Journal of Clinical Immunology

Lymphoid NeoplasiaMedicineImmunologyImmune Checkpoint InhibitorPrimary B-cll Resistance +5

The co‐expression of 2B4 (CD244) and CD160 delineates a subpopulation of human CD8⁺ T cells with a potent CD160‐mediated cytolytic effector function

Jérôme Rey, Jérôme Giustiniani, Françoise Mallet, +5

European Journal of Immunology

Cd8+ TT-regulatory CellImmune RegulationImmunologyImmunologic Mechanism +17

Stimulation of non-Hodgkin's lymphoma via HVEM: an alternate and safe way to increase Fas-induced apoptosis and improve tumor immunogenicity

Régis Costello, Françoise Mallet, Bernadette Barbarat, +5

Leukemia

Tumor BiologyLymphoid NeoplasiaTumor ImmunogenicityCancer ImmunosurveillanceFas-induced Apoptosis +12

Interleukin-7 is a potent co-stimulus of the adhesion pathway involving CD2 and CD28 molecules.

Régis Costello, Hervé Brailly, Françoise Mallet, +2

PubMed

Adhesion PathwayHealthy Blood DonorsCell AdhesionT-regulatory CellImmunology +18