Recombinant HCV Variants With NS5A From Genotypes 1–7 Have Different Sensitivities to an NS5A Inhibitor but Not Interferon-α

Troels K. H. Scheel, Judith M. Gottwein, Lotte S. Mikkelsen, +2

Gastroenterology

Recombinant Hcv VariantsMolecular VirologyViral HepatitisImmunologyAntiviral Therapy +8

Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1–7 and Escape Variants

Judith M. Gottwein, Long V. Pham, Lotte S. Mikkelsen, +5

Gastroenterology

Escape VariantsViral HepatitisMedicineAntiviral Drug DevelopmentAntiviral Therapy +4

Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication

Santseharay Ramírez, Carlota Fernandez-Antunez, Andrea Galli, +13

Antimicrobial Agents and Chemotherapy

Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains

Yi‐Ping Li, Santseharay Ramírez, Judith M. Gottwein, +4

Proceedings of the National Academy of Sciences

Viral ReplicationInfectious CulturesHepatitis C VirusSynthetic VirologyImmunology +15

Breadth of neutralization and synergy of clinically relevant human monoclonal antibodies against HCV genotypes 1a, 1b, 2a, 2b, 2c, and 3a

Thomas H. R. Carlsen, Jannie Pedersen, Jannick Prentoe, +6

Hepatology

Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir

Santseharay Ramírez, Lotte S. Mikkelsen, Judith M. Gottwein, +1

Gastroenterology

Viral EvolutionMolecular VirologyEscape VariantsPathogenesisHepatitis +6

Productive Homologous and Non-homologous Recombination of Hepatitis C Virus in Cell Culture

Troels K. H. Scheel, Andrea Galli, Yi‐Ping Li, +3

PLoS Pathogens

Viral ReplicationHcv RecombinationHepatitis C VirusViral Polymerase MechanismImmunology +14

Efficient Infectious Cell Culture Systems of the Hepatitis C Virus (HCV) Prototype Strains HCV-1 and H77

Yi‐Ping Li, Santseharay Ramírez, Lotte S. Mikkelsen, +1

Journal of Virology

Analysis of Functional Differences between Hepatitis C Virus NS5A of Genotypes 1–7 in Infectious Cell Culture Systems

Troels K. H. Scheel, Jannick Prentoe, Thomas H. R. Carlsen, +3

PLoS Pathogens

Genotypes 1–7Viral ReplicationHepatitis C VirusViral Polymerase MechanismImmunology +15

Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication

Ulrik Fahnøe, Long V. Pham, Carlota Fernandez-Antunez, +9

Viruses