Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity

Rachid Essalmani, Jaspreet Jain, Delia Susan‐Resiga, +15

Journal of Virology

Co-delivery of miR-181a and melphalan by lipid nanoparticles for treatment of seeded retinoblastoma

Seyed Nasrollah Tabatabaei, Rabeb Mouna Derbali, Chun Yang, +4

Journal of Controlled Release

NanoparticlesEngineeringImmunologyLipid NanoparticlesExtracellular Microvesicles +17

Aptamer-based liposomes improve specific drug loading and release

Kevin Plourde, Rabeb Mouna Derbali, Arnaud Desrosiers, +3

Journal of Controlled Release

PharmacologyDrug TargetingBiomolecular EngineeringAptamer-based Liposomes

Cationic switchable lipids: pH-triggered molecular switch for siRNA delivery

Warren Viricel, Steve Poirier, Amira Mbarek, +2

Nanoscale

Lipid PreparationNanomedicineEngineeringEndosomal Ph ValuesBiochemistry +9

Tailored Nanocarriers for the Pulmonary Delivery of Levofloxacin against <i>Pseudomonas aeruginosa</i>: A Comparative Study

Rabeb Mouna Derbali, Valéry Aoun, Ghina Moussa, +6

Molecular Pharmaceutics

Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin

Delia Susan‐Resiga, Emmanuelle Girard, Rachid Essalmani, +8

Journal of Biological Chemistry

Modulation of the Passive Permeability of Semipeptidic Macrocycles: N- and C-Methylations Fine-Tune Conformation and Properties

Christian Comeau, Benjamin Ries, Thomas Stadelmann, +11

Journal of Medicinal Chemistry

Peptide EngineeringMethyl Substitution VariesOrganic ChemistryC-methylations Fine-tune ConformationChemical Biology +17

Survivin silencing improved the cytotoxicity of carboplatin and melphalan in Y79 and primary retinoblastoma cells

Victor Passos Gibson, Rabeb Mouna Derbali, Huu Trong Phan, +4

International Journal of Pharmaceutics

Chemoprevention StrategyMedicineCell ProliferationPrimary Retinoblastoma CellsRadiation Oncology +4

Programmable self-regulated molecular buffers for precise sustained drug delivery

Arnaud Desrosiers, Rabeb Mouna Derbali, Sami Hassine, +8

Nature Communications

SARS-CoV-2 spike-glycoprotein processing at S1/S2 and S2’and shedding of the ACE2 viral receptor: roles of Furin and TMPRSS2 and implications for viral infectivity and cell-to-cell fusion

Rachid Essalmani, Jaspreet Jain, Delia Susan‐Resiga, +15

Protein SecretionTmprss2 InhibitorsSars-cov-2 Spike-glycoprotein ProcessingViral PathogenesisAnalytical Ultracentrifugation +19