Ruud K. B. Schuurman

The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages

Michel de Weers, Martie C. M. Verschuren, Margriet E. M. Kraakman et al. · European Journal of Immunology · 1993 · 204 citations

B-cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked agammaglobulinemia.

Michel de Weers, Gaby Brouns, Steve Hinshelwood et al. · Journal of Biological Chemistry · 1994 · 183 citations · Full text

Mutation analysis of the Bruton's tyrosine kinase gene in X-linked agammaglobulinemia: identification of a mutation which affects the same codon as is altered in immunodeficient xid mice

Michel de Weers, Rob G.J. Mensink, Margriet E. M. Kraakman et al. · Human Molecular Genetics · 1994 · 126 citations

X-linked Agammaglobulinemia, Genetics, Tyrosine Kinase +19

Polyclonal activation of human lymphocytes <i>in vitro</i>. I. Characterization of the lymphocyte response to a T cell-independent B cell mitogen.

Ruud K. B. Schuurman, Erwin W. Gelfand, Hans‐Michael Dosch · The Journal of Immunology · 1980 · 124 citations

Restricted utilization of germ‐line V_H3 genes and short diverse third complementarity‐determining regions (CDR3) in human fetal B lymphocyte immunoglobulin heavy chain rearrangements

Frank M. Raaphorst, Erik Timmers, Marcel Kenter et al. · European Journal of Immunology · 1992 · 87 citations