Daniel Klewinghaus

Grabbing the Bull by Both Horns: Bovine Ultralong CDR-H3 Paratopes Enable Engineering of ‘Almost Natural’ Common Light Chain Bispecific Antibodies Suitable For Effector Cell Redirection

Daniel Klewinghaus, Lukas Pekar, Paul Arras et al. · Frontiers in Immunology · 2022 · 26 citations · Full text

Pharmacy, Biotechnology, Immunology +17

<scp>NKp46</scp>‐specific single domain antibodies enable facile engineering of various potent <scp>NK</scp> cell engager formats

Britta Lipinski, Paul Arras, Lukas Pekar et al. · Protein Science · 2023 · 23 citations · Full text

Pharmacy, Immunology, Oncology +17

Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity

Lukas Pekar, Daniel Klewinghaus, Paul Arras et al. · Frontiers in Immunology · 2021 · 19 citations · Full text

Pharmacy, Immunology, Oncology +17

A library approach for the <i>de novo</i> high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

Paul Arras, Han Byul Yoo, Lukas Pekar et al. · mAbs · 2023 · 19 citations · Full text

Pharmacy, Biotechnology, Immunology +17