Makoto Kawashima

Decreased Level of Ceramides in Stratum Corneum of Atopic Dermatitis: An Etiologic Factor in Atopic Dry Skin?

Genji Imokawa, Akihito Abe, Kumi Jin et al. · Journal of Investigative Dermatology · 1991 · 1K citations

Medicine, Biochemistry, Dermatology +16

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

Diamant Thaçi, Eric L. Simpson, Lisa A. Beck et al. · The Lancet · 2015 · 566 citations

Life Sciences, Dermatology, Immunology +11

Trial of Nemolizumab and Topical Agents for Atopic Dermatitis with Pruritus

Kenji Kabashima, Takayo Matsumura, Hiroshi Komazaki et al. · New England Journal of Medicine · 2020 · 353 citations · Full text

Medicine, Dermatology, Pharmacology +17

Decreased Levels of Sphingosine, a Natural Antimicrobial Agent, may be Associated with Vulnerability of the Stratum Corneum from Patients with Atopic Dermatitis to Colonization by Staphylococcus aureus

Junko Arikawa, Mutsumi Ishibashi, Makoto Kawashima et al. · Journal of Investigative Dermatology · 2002 · 269 citations

Medicine, Dermatology, Immunology +17

High-Expression of Sphingomyelin Deacylase is an Important Determinant of Ceramide Deficiency Leading to Barrier Disruption in Atopic Dermatitis1

Junko Hara, Kazuhiko Higuchi, Reiko Okamoto et al. · Journal of Investigative Dermatology · 2000 · 228 citations · Full text

Medicine, Biochemistry, Dermatology +17