Lauris E. Kemp

Biosynthesis of isoprenoids: Crystal structure of 4-diphosphocytidyl-2C-methyl- <scp>d</scp> -erythritol kinase

L. Miallau, M.S. Alphey, Lauris E. Kemp et al. · Proceedings of the National Academy of Sciences · 2003 · 97 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structure of 2C-methyl- <scp>d</scp> -erythritol 2,4- cyclodiphosphate synthase: An essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development

Lauris E. Kemp, Charles S. Bond, William N. Hunter · Proceedings of the National Academy of Sciences · 2002 · 81 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

The identification of isoprenoids that bind in the intersubunit cavity of<i>Escherichia coli</i>2<i>C</i>-methyl-<scp>D</scp>-erythritol-2,4-cyclodiphosphate synthase by complementary biophysical methods

Lauris E. Kemp, M.S. Alphey, Charles S. Bond et al. · Acta Crystallographica Section D Biological Crystallography · 2004 · 41 citations · Full text

Life Sciences, Biochemistry, Microbiology +12

Structure of a tetragonal crystal form of<i>Escherichia coli</i>2-<i>C</i>-methyl-<scp>D</scp>-erythritol 4-phosphate cytidylyltransferase

Lauris E. Kemp, Charles S. Bond, William N. Hunter · Acta Crystallographica Section D Biological Crystallography · 2003 · 34 citations

Life Sciences, Biochemistry, Microbiology +14

A double mutation of<i>Escherichia coli</i>2<i>C</i>-methyl-<scp>D</scp>-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate

Tanja Sgraja, Lauris E. Kemp, Nicola L. Ramsden et al. · Acta Crystallographica Section F Structural Biology and Crystallization Communications · 2005 · 15 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17