Eliazar Rodriguez-Garcı́a

The first synthesis of substituted azepanes mimicking monosaccharides: a new class of potent glycosidase inhibitors

Hongqing Li, Yves Blériot, Caroline Chantereau et al. · Organic & Biomolecular Chemistry · 2004 · 85 citations · Full text

Bioorganic Chemistry, Glycobiology, Seven-membered Ring Iminoalditols +17

Derivatives of (2R,3R,4S)-2-Aminomethylpyrrolidine-3,4-diol are selective α-Mannosidase inhibitors

Florence Popowycz, Sandrine Gerber‐Lemaire, Raynald Demange et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 54 citations · Full text

Medicinal Chemistry, Derivative (Chemistry), Derivatives +6

An Efficient Combinatorial Method for the Discovery of Glycosidase Inhibitors The concept and part of the text of this work were presented at the XIth Eurocarb Conference in Lisbon on September 7, 2001, under the title “An Efficient Combinatorial Method for the Discovery of Glycosidase Inhibitors. Imines Equilibrating with (2R,3R,4S)-2-Aminomethyl pyrrolidine-3,4-diol and Aldehydes are Inhibitors of α-Mannosidases and Models for the Inhibitory Activity of Corresponding Amines”.

Sandrine Gerber‐Lemaire, Florence Popowycz, Eliazar Rodriguez-Garcı́a et al. · ChemBioChem · 2002 · 48 citations · Full text

Bioorganic Chemistry, Glycobiology, Quantitative Pharmacology +22

New 1-amino-1-deoxy- and 2-amino-2-deoxy-polyhydroxyazepanes: synthesis and inhibition of glycosidases

Hongqing Li, Yves Blériot, Jean‐Maurice Mallet et al. · Tetrahedron Asymmetry · 2005 · 31 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +6

Synthesis and <i>α</i>‐Mannosidase Inhibitory Evaluation of (2<i>R</i>,3<i>R</i>,4<i>S</i>)‐ and (2<i>S</i>,3<i>R</i>,4<i>S</i>)‐2‐(Aminomethyl)pyrrolidine‐3,4‐diol Derivatives

Florence Popowycz, Sandrine Gerber‐Lemaire, Eliazar Rodriguez-Garcı́a et al. · Helvetica Chimica Acta · 2003 · 31 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Jack Bean +13