Sarah F. Douglas

Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7)

Chakravarthi Simhadri, Kevin D. Daze, Sarah F. Douglas et al. · Journal of Medicinal Chemistry · 2014 · 107 citations · Full text

Drug Target, Peptide-driven Approach, Molecular Biology +19

Mechanically stable fibrin scaffolds promote viability and induce neurite outgrowth in neural aggregates derived from human induced pluripotent stem cells

Meghan Robinson, Sarah F. Douglas, Stephanie M. Willerth · Scientific Reports · 2017 · 61 citations · Full text

A phase I trial of pantoprazole in combination with doxorubicin in patients with advanced solid tumors: evaluation of pharmacokinetics of both drugs and tissue penetration of doxorubicin

Irene Braña, Alberto Ocaña, Eric X. Chen et al. · Investigational New Drugs · 2014 · 54 citations

Oncology, Tissue Penetration, Pharmacology +6

Selective Inhibition of CBX6: A Methyllysine Reader Protein in the Polycomb Family

Natalia Milosevich, Michael C. Gignac, James McFarlane et al. · ACS Medicinal Chemistry Letters · 2015 · 53 citations · Full text

Selective Inhibition, Molecular Recognition, Medicinal Chemistry +15

Synthetic trimethyllysine receptors that bind histone 3, trimethyllysine 27 (H3K27me3) and disrupt its interaction with the epigenetic reader protein CBX7

Sara Tabet, Sarah F. Douglas, Kevin D. Daze et al. · Bioorganic & Medicinal Chemistry · 2013 · 40 citations

Histone Modifications, Chromatin, Chromatin Remodeling +10