Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics

Prashant Dogra, Natalie L. Adolphi, Zhihui Wang, +9

Nature Communications

A mathematical model to predict nanomedicine pharmacokinetics and tumor delivery

Prashant Dogra, Joseph D. Butner, Javier Ruiz-Ramírez, +5

Computational and Structural Biotechnology Journal

Intratumoral injection of hydrogel-embedded nanoparticles enhances retention in glioblastoma

Giulia Brachi, Javier Ruiz-Ramírez, Prashant Dogra, +8

Nanoscale

Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release

Hitomi Hosoya, Andrey S. Dobroff, Wouter H. P. Driessen, +19

Proceedings of the National Academy of Sciences

Theory and Experimental Validation of a Spatio-temporal Model of Chemotherapy Transport to Enhance Tumor Cell Kill

Zhihui Wang, Romica Kerketta, Yao-Li Chuang, +13

PLoS Computational Biology

Mathematical modeling of cancer immunotherapy for personalized clinical translation

Joseph D. Butner, Prashant Dogra, Caroline Chung, +5

Nature Computational Science

Clinical TranslationMedicineImmunologyImmunoeditingPersonalized Clinical Translation +3

A mathematical model for the quantification of a patient’s sensitivity to checkpoint inhibitors and long-term tumour burden

Joseph D. Butner, Zhihui Wang, Dalia Elganainy, +13

Nature Biomedical Engineering

Long-term Tumour BurdenMedicineCancer ManagementMathematical ModelImmune Checkpoint Inhibitor +5

Size‐Optimized Ultrasmall Porous Silica Nanoparticles Depict Vasculature‐Based Differential Targeting in Triple Negative Breast Cancer

Shreya Goel, Carolina A. Ferreira, Prashant Dogra, +8

Small

NanoparticlesNanotherapeuticsEngineeringDifferential TargetingBiomedical Engineering +18

Innate Immunity Plays a Key Role in Controlling Viral Load in COVID-19: Mechanistic Insights from a Whole-Body Infection Dynamics Model

Prashant Dogra, Javier Ruiz-Ramírez, Kavya Sinha, +9

ACS Pharmacology & Translational Science

Understanding Drug Resistance in Breast Cancer with Mathematical Oncology

Terisse Brocato, Prashant Dogra, Eugene J. Koay, +4

Current Breast Cancer Reports

Breast OncologyMedicinePharmacologyBreast CancerOncology +2