CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas

Joseph Flores‐Toro, Defang Luo, Adithya Gopinath, +9

Proceedings of the National Academy of Sciences

Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27.

Defang Luo, Marilyn M. Bui, Andrew Muir, +3

PubMed

TGF-β1 upregulates CX3CR1 expression and inhibits fractalkine-stimulated signaling in rat microglia

Shuzhen Chen, Defang Luo, Wolfgang J. Streit, +1

Journal of Neuroimmunology

InflammationSignal TransductionMedicineRat MicrogliaImmune Regulation +8

Chemokine receptor CXCR3 promotes growth of glioma

Che Liu, Defang Luo, Brent A. Reynolds, +6

Carcinogenesis

Angiotensin II Regulation of Proliferation, Differentiation, and Engraftment of Hematopoietic Stem Cells

Seungbum Kim, Michael Zingler, Jeffrey K. Harrison, +4

Hypertension

Angiotensin Ii RegulationAng Ii InfusionAdult Stem CellImmunologyBlood Cell +16

Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+/CX3CR1+ M-MDSCs into the tumor microenvironment in a redundant manner

Gregory P. Takacs, Christian J. Kreiger, Defang Luo, +5

Frontiers in Immunology

CX3CL1 and CX3CR1 in the GL261 murine model of glioma: CX3CR1 deficiency does not impact tumor growth or infiltration of microglia and lymphocytes

Che Liu, Defang Luo, Wolfgang J. Streit, +1

Journal of Neuroimmunology

Cx3cr1 DeficiencyGliomaMedicineTumor GrowthImmunology +8

CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes

Eleni Beli, James M. Dominguez, Ping Hu, +13

Journal of Molecular Medicine

Type 1Diabetic RetinopathyOcular DiseaseRetinaCx3cr1 Deficiency +8

Spontaneous and Fas-mediated apoptosis are diminished in umbilical cord blood neutrophils compared with adult neutrophils

Bernhard Allgaier, Min Shi, Defang Luo, +1

Journal of Leukocyte Biology

CCL5, CCR1 and CCR5 in murine glioblastoma: Immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5

Kien Pham, Defang Luo, Che Liu, +1

Journal of Neuroimmunology

Neuro-oncologyIndividual ExpressionCancer ImmunosurveillanceMedicineImmunology +8