Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation

Andreas‐David Brunner, Marvin Thielert, Catherine G. Vasilopoulou, +14

Molecular Systems Biology

Proteomic TechnologySingle Cell SequencingMedicineNatural SciencesProteomics +9

Deep Visual Proteomics defines single-cell identity and heterogeneity

Andreas Mund, Fabian Coscia, András Kriston, +18

Nature Biotechnology

EngineeringPathologyCell CultureSpatial OmicsTumor Biology +14

Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

Sara C. Buch-Larsen, Kathrine B. Sylvestersen, Andreas Mund, +6

Science Signaling

Epigenetic ChangeGeneticsMolecular BiologyEpigeneticsSplicing Variant +18

A streamlined mass spectrometry–based proteomics workflow for large‐scale FFPE tissue analysis

Fabian Coscia, Sophia Doll, Jacob Mathias Bech, +7

The Journal of Pathology

Biological Mass SpectrometryPathologyProteomic TechnologyClinical DiagnosisBiostatistics +15

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

Fabian Coscia, Ernst Lengyel, Jaikumar Duraiswamy, +12

Cell

OncologyImmunotherapy TargetChemosensitivity MediatorMedicineCancer Genomics +6

Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome

Florian A. Rosenberger, Marvin Thielert, Maximilian T. Strauss, +14

Nature Methods

Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation

Andreas‐David Brunner, Marvin Thielert, Catherine G. Vasilopoulou, +14

Biological Mass SpectrometryMolecular BiologyCell CycleProteomic TechnologySingle Cell Sequencing +17

Loss of <i>CHD1</i> causes DNA repair defects and enhances prostate cancer therapeutic responsiveness

Vijayalakshmi Kari, Wael Mansour, Sanjay Kumar Raul, +9

EMBO Reports

ChromatinGenome InstabilityMedicineNatural SciencesDna Repair Defects +8

Spatial proteomics identifies JAKi as treatment for a lethal skin disease

Thierry M. Nordmann, Holly Anderton, Akito Hasegawa, +30

Nature

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes

Sabrina Schreiner, Carolin Bürck, Peter Groitl, +5

Nucleic Acids Research