Charles A. McWherter

A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis

Gideon M. Hirschfield, Christopher L. Bowlus, Marlyn J. Mayo et al. · New England Journal of Medicine · 2024 · 192 citations

Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study

David Jones, Pol Boudes, Mark G. Swain et al. · ˜The œLancet. Gastroenterology & hepatology · 2017 · 181 citations

Molecular Pharmacology, Selective Ppar-δ Agonist, Hepatology +11

Kinetic and structural evidence for a sequential ordered Bi Bi mechanism of catalysis by Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

David A. Rudnick, Charles A. McWherter, Warren J. Rocque et al. · Journal of Biological Chemistry · 1991 · 148 citations · Full text

Engineering, Molecular Biology, Chemical Biology +17

Genetic studies reveal that myristoylCoA:protein N‐myristoyltransferase is an essential enzyme in <i>Candida albicans</i>

Robin A. Weinberg, Charles A. McWherter, Sandra K. Freeman et al. · Molecular Microbiology · 1995 · 122 citations

A comparative analysis of the kinetic mechanism and peptide substrate specificity of human and Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

Warren J. Rocque, Charles A. McWherter, David C. Wood et al. · Journal of Biological Chemistry · 1993 · 108 citations · Full text

Molecular Biology, Chemical Biology, Saccharomyces Cerevisiae Myristoyl-coa +20