Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression

Xinyi Wang, Guangqiang Sun, Teng Feng, +23

Cell Research

Single-cell RNA-sequencing atlas reveals an MDK-dependent immunosuppressive environment in ErbB pathway-mutated gallbladder cancer

Yijian Zhang, Chunman Zuo, Liguo Liu, +36

Journal of Hepatology

Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis

Zhiping Liu, Siyuan Yan, Jiaojiao Wang, +27

Nature Communications

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation

Yiming Xu, Yong Wang, Siyuan Yan, +16

Nature Communications

Fecal microbiota characteristics of Chinese patients with primary IgA nephropathy: a cross-sectional study

Xiaofang Hu, Jie Du, Yuhong Xie, +6

BMC Nephrology

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis

Yiming Xu, Yong Wang, Siyuan Yan, +21

EMBO Molecular Medicine

Akt inhibition attenuates rasfonin-induced autophagy and apoptosis through the glycolytic pathway in renal cancer cells

Qiumin Lu, Siyuan Yan, Hui Sun, +6

Cell Death and Disease

The PPARγ agonist Troglitazone induces autophagy, apoptosis and necroptosis in bladder cancer cells

Siyuan Yan, Xin Yang, Tuo Chen, +2

Cancer Gene Therapy

Tumor BiologyCell AutophagySignaling PathwayPparγ Agonist TroglitazoneMedicine +9

PFKFB3 Inhibition Attenuates Oxaliplatin-Induced Autophagy and Enhances Its Cytotoxicity in Colon Cancer Cells

Siyuan Yan, Nan Zhou, Deru Zhang, +4

International Journal of Molecular Sciences

MitophagyChemoprevention StrategyApoptosisCell DeathCancer Biology +17

Long-term exposure to genistein inhibits the proliferation of gallbladder cancer by downregulating the MCM complex

Yajun Geng, Shili Chen, Yang Yang, +49

Science Bulletin

Mcm ComplexPlasma Soy Isoflavone-genisteinOncologyChemoprevention StrategyGastrointestinal Oncology +12