Linus J. Conrad

Rare NaV1.7 variants associated with painful diabetic peripheral neuropathy

Iulia Blesneac, Andreas C. Themistocleous, Carl Fratter et al. · Pain · 2017 · 135 citations · Full text

A pharmacological master key mechanism that unlocks the selectivity filter gate in K ⁺ channels

Marcus Schewe, Han Sun, Ümit Mert et al. · Science · 2019 · 131 citations · Full text

A lower X-gate in TASK channels traps inhibitors within the vestibule

Karin E. J. Rödström, Aytuğ K. Kiper, Wei Zhang et al. · Nature · 2020 · 93 citations

Central Vestibular System, Neural Mechanism, Vestibular System +13

Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel

Prafulla Aryal, Viwan Jarerattanachat, Michael V. Clausen et al. · Structure · 2017 · 84 citations · Full text

Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate

Peter Proks, Marcus Schewe, Linus J. Conrad et al. · The Journal of General Physiology · 2021 · 34 citations · Full text

Multiple Mechanisms, Molecular Biology, Chemical Biology +21