Ryan E. Loy

Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca ²⁺ ·calmodulins

Jennifer L. Fallon, Mariah R. Baker, Liangwen Xiong et al. · Proceedings of the National Academy of Sciences · 2009 · 107 citations · Full text

Cardiac Muscle, Crystal Structure, Molecular Biology +18

Multi-minicore disease and atypical periodic paralysis associated with novel mutations in the skeletal muscle ryanodine receptor (RYR1) gene

Haiyan Zhou, Suzanne Lillis, Ryan E. Loy et al. · Neuromuscular Disorders · 2010 · 88 citations · Full text

Muscle Function, Skeletal Muscle, Physiology +8

An <i>Ryr1</i> ^{<i>I4895T</i>} mutation abolishes Ca ²⁺ release channel function and delays development in homozygous offspring of a mutant mouse line

Elena Zvaritch, Frederic Depreux, Natasha Kraeva et al. · Proceedings of the National Academy of Sciences · 2007 · 80 citations · Full text

Muscle weakness in <i>Ryr1I4895T/WT</i> knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum

Ryan E. Loy, Murat Orynbayev, Le Xu et al. · The Journal of General Physiology · 2010 · 76 citations · Full text

The I4895T mutation in the type 1 ryanodine receptor induces fiber‐type specific alterations in skeletal muscle that mimic premature aging

Simona Boncompagni, Ryan E. Loy, Robert T. Dirksen et al. · Aging Cell · 2010 · 43 citations · Full text

Cardiac Muscle, Muscle Function, Mechanotransduction +17