The Human Cathelicidin LL-37 Modulates the Activities of the P2X7 Receptor in a Structure-dependent Manner

Linda Tomasinsig, Cinzia Pizzirani, Barbara Skerlavaj, +5

Journal of Biological Chemistry

ImmunologyCell DeathStructure-dependent MannerCell ProliferationPharmacotherapy +22

Extracellular ATP Exerts Opposite Effects on Activated and Regulatory CD4+ T Cells via Purinergic P2 Receptor Activation

Sara Trabanelli, Darina Očadlíková, Sara Gulinelli, +7

The Journal of Immunology

Increased P2X7 Receptor Expression and Function in Thyroid Papillary Cancer: A New Potential Marker of the Disease?

Anna Solini, Sabina Cuccato, Davide Ferrari, +8

Endocrinology

The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration

Lara Rossi, Rossella Manfredini, Francesco Bertolini, +11

Blood

IL‐18 associates to microvesicles shed from human macrophages by a LPS/TLR‐4 independent mechanism in response to P2X receptor stimulation

Sara Gulinelli, Erica Salaro, Marta Vuerich, +6

European Journal of Immunology

Il‐18 AssociatesMicrobial PathogensInnate Immune SystemImmunologyImmune Regulation +20

Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines

Davide Ferrari, Sara Gulinelli, Valentina Salvestrini, +11

Experimental Hematology

Regenerative MedicineInflammationPurinergic StimulationHoming CapacityMedicine +10

ATP secreted by endothelial cells blocks CX3CL1-elicited natural killer cell chemotaxis and cytotoxicity via P2Y11 receptor activation

Stefania Gorini, G Callegari, Giulia Romagnoli, +10

Blood

Stimulation of Purinergic Receptors Modulates Chemokine Expression in Human Keratinocytes

Saveria Pastore, Francesca Mascia, Sara Gulinelli, +6

Journal of Investigative Dermatology

InflammationSkin DevelopmentSignal TransductionMolecular PhysiologyCutaneous Biology +8

Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice

Valentina Salvestrini, Roberta Zini, Lara Rossi, +15

Blood

Modulation of P2X₇ receptor functions by polymyxin B: crucial role of the hydrophobic tail of the antibiotic molecule

Davide Ferrari, Cinzia Pizzirani, Sara Gulinelli, +5

British Journal of Pharmacology