Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer

William M. Grady, Rachael K. Parkin, Patrick S. Mitchell, +12

Oncogene

Systems BiologyIntronic Microrna Hsa-mir-342Host Gene EvlColorectal CancerPathology +7

Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn

Stuart J. Spechler, John G. Hunter, Karen Jones, +36

New England Journal of Medicine

Cardiothoracic SurgeryAntireflux SurgeryCardiovascular DiseaseMedicineGastroenterology +10

Differences in DNA Methylation Signatures Reveal Multiple Pathways of Progression From Adenoma to Colorectal Cancer

Yanxin Luo, Chao-Jen Wong, Andrew M. Kaz, +12

Gastroenterology

Tumor BiologyChromatinMedicineEpigenetic ChangeDna Methylation +11

NTRK3 Is a Potential Tumor Suppressor Gene Commonly Inactivated by Epigenetic Mechanisms in Colorectal Cancer

Yanxin Luo, Andrew M. Kaz, Samornmas Kanngurn, +6

PLoS Genetics

Tumor BiologyEpigenetic RegulationMedicineDependence ReceptorPathology +13

Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age

Andrew M. Kaz, Chao-Jen Wong, Slavomir Dzieciatkowski, +3

Epigenetics

Epigenetic ChangeGeneticsDna MethylationGastroenterologyPathology +23

BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis

Bobak Parang, Andrew M. Kaz, Caitlyn W. Barrett, +17

Gut

DNA methylation profiling in Barrett’s esophagus and esophageal adenocarcinoma reveals unique methylation signatures and molecular subclasses

Andrew M. Kaz, Chao-Jen Wong, Yanxin Luo, +6

Epigenetics

Esophageal CancerEpigenetic ChangeGeneticsDna MethylationGastroenterology +18

Subtypes of Barrett’s oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis

Ming Yu, Sean K. Maden, Matthew D. Stachler, +15

Gut

Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans

Johanna W. Lampe, Eunji Kim, Lisa Levy, +12

American Journal of Clinical Nutrition

ProbioticDysbiosisFecal Microbiome ResponseGut MicrobiologyPathology +8

A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett’s Esophagus

Kit Curtius, Chao-Jen Wong, William D. Hazelton, +5

PLoS Computational Biology

Esophageal CancerAgingPrognosisEpidemiology Of CancerGastroenterology +16