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Ta-Chung Yu, Fangfang Guo, Yanan Yu, +12

Cell

Tumor BiologyCell AutophagyAutophagyColorectal CancerPathology +4

Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

Dongjun Peng, Ilona Kryczek, Nisha Nagarsheth, +15

Nature

Epigenetic SilencingTumor ImmunologyCancer ImmunosurveillanceImmunologyTumor Immunity +5

IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L

Ilona Kryczek, Yanwei Lin, Nisha Nagarsheth, +13

Immunity

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PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer

Nisha Nagarsheth, Dongjun Peng, Ilona Kryczek, +15

Cancer Research

Cancer ImmunosurveillanceEpigenetic RegulationMedicineImmunologyTumor Immunity +10

An Analog of the Natural Steroidal Alkaloid Cortistatin A Potently Suppresses Tat-Dependent HIV Transcription

Guillaume Mousseau, Mark A. Clementz, Wendy Bakeman, +7

Cell Host & Microbe

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IL33 Promotes Colon Cancer Cell Stemness via JNK Activation and Macrophage Recruitment

Min Fang, Yongkui Li, Kai Huang, +19

Cancer Research

Resistance to the Tat Inhibitor Didehydro-Cortistatin A Is Mediated by Heightened Basal HIV-1 Transcription

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mBio

Th22 cells control colon tumorigenesis through STAT3 and Polycomb Repression complex 2 signaling

Danfeng Sun, Yanwei Lin, Jie Hong, +8

OncoImmunology

PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages

Michael Pitter, Ilona Kryczek, Hongjuan Zhang, +14

Cell Reports

Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

Ilona Kryczek, Dongjun Peng, Nisha Nagarsheth, +10

The Journal of Immunology

Histone ModificationsEpigenetic ChangeDna MethylationImmunologyImmunoediting +14