Dorothea Bestle

Statistics

Publications

Citations

1.2K

H-Index

Active since

2019

Affiliations

Oregon State University(Current)

Philipps University of Marburg

Fraunhofer Institute for Molecular Biology and Applied Ecology

German Center for Infection Research

Dorothea Bestle is an author at Oregon State University specializing in infectious diseases, host protease-mediated viral protein cleavage, and viral proteases.

Publications per year

2019–2024

Publications

TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

Dorothea Bestle, Miriam Ruth Heindl, Hannah Limburg et al. · Life Science Alliance · 2020 · 849 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +13

TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes

Hannah Limburg, Anne Harbig, Dorothea Bestle et al. · Journal of Virology · 2019 · 192 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets

Dorothea Bestle, Miriam Ruth Heindl, Hannah Limburg et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 122 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +17

Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells

Dorothea Bestle, Hannah Limburg, Diana Kruhl et al. · Journal of Virology · 2021 · 40 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells

Miriam Ruth Heindl, Anna-Lena Rupp, Marie Schwerdtner et al. · Journal of Virology · 2024 · 10 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

1–5 of 5