Kathleen L. Tivel

Pharmacokinetic properties of several novel oligonucleotide analogs in mice.

Stanley T. Crooke, Melissa Graham, J E Zuckerman et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 228 citations

Base-Sequence Dependence of Emission Lifetimes for D141018-30-6NA Oligomers and Duplexes Covalently Labeled with Pyrene: Relative Electron-Transfer Quenching Efficiencies of A, G, C, and T Nucleosides toward Pyrene

Muthiah Manoharan, Kathleen L. Tivel, Min Zhao et al. · The Journal of Physical Chemistry · 1995 · 181 citations

Base-sequence Dependence, Emission Lifetimes, Engineering +17

Inhibition of expression of the multidrug resistance-associated P-glycoprotein of by phosphorothioate and 5' cholesterol-conjugated phosphorothioate antisense oligonucleotides.

Suresh K. Alahari, Nicholas M. Dean, M. H. FISHER et al. · Molecular Pharmacology · 1996 · 97 citations

Lipidic nucleic acids

Muthiah Manoharan, Kathleen L. Tivel, P. Dan Cook · Tetrahedron Letters · 1995 · 45 citations

Nucleic Acid Chemistry, Biochemistry, Natural Sciences +4

Introduction of a lipophilic thioether tether in the minor groove of nucleic acids for antisense applications

Muthiah Manoharan, Laura K. Johnson, Kathleen L. Tivel et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 30 citations

Nucleic Acid Chemistry, Bioorganic Chemistry, Biochemistry +6