Christelle Castell

Discovery of (2<i>S</i>)-8-[(3<i>R</i>)-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2<i>H</i>-pyrimido[1,2-<i>a</i>]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

Benoit Pasquier, Youssef El‐Ahmad, Bruno Filoche-Rommé et al. · Journal of Medicinal Chemistry · 2014 · 92 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Inhibition of the Ras-Net (Elk-3) Pathway by a Novel Pyrazole that Affects Microtubules

Christine Wasylyk, Hong Zheng, Christelle Castell et al. · Cancer Research · 2008 · 76 citations · Full text

Life Sciences, Oncology, Pharmacology +17

First‐in‐human trial of the PI3Kβ‐selective inhibitor SAR260301 in patients with advanced solid tumors

Philippe L. Bédard, Michael A. Davies, Scott Kopetz et al. · Cancer · 2017 · 34 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15

Phase I Dose-Escalation Study of Pilaralisib (SAR245408, XL147) in Combination with Paclitaxel and Carboplatin in Patients with Solid Tumors

Jennifer J. Wheler, David G. Mutch, Joanne Lager et al. · The Oncologist · 2017 · 30 citations · Full text

Medicine, Oncology, Pharmacology +12

The Selective Intravenous Inhibitor of the MET Tyrosine Kinase SAR125844 Inhibits Tumor Growth in <i>MET</i> -Amplified Cancer

Coumaran Égile, Mireille Kenigsberg, Christine Delaisi et al. · Molecular Cancer Therapeutics · 2014 · 28 citations · Full text

Medicine, Oncology, Pharmacology +17