Peter W. Melera

Isolation of amplified and overexpressed DNA sequences from adriamycin-resistant human breast cancer cells.

C.R. Fairchild, S. Percy Ivy, C. S. Kao-Shan et al. · PubMed · 1987 · 297 citations

Breast Oncology, Dna Analysis, Molecular Biology +22

Amplification and Expression of Genes Associated with Multidrug Resistance in Mammalian Cells

Kathleen W. Scotto, June L. Biedler, Peter W. Melera · Science · 1986 · 291 citations

Antimicrobial Resistance Gene, Signal Transduction, Genes Associated +15

Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance.

Scott E. Devine, Victor Ling, Peter W. Melera · Proceedings of the National Academy of Sciences · 1992 · 142 citations · Full text

Proteinlipid Interaction, Cytoskeleton, Amino Acid Substitutions +20

Gene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells.

Marian B. Meyers, Barbara A. Spengler, Tien-Lin Chang et al. · The Journal of Cell Biology · 1985 · 100 citations · Full text

Cytogenetics, Genetics, Gene Characterization +17

Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases.

Peter W. Melera, John A. Lewis, June L. Biedler et al. · Journal of Biological Chemistry · 1980 · 98 citations · Full text

Molecular Weight Form, Cdna Probe Specific, Genetics +17