Tyler D. Baguley

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease

Jian Xu, Manavi Chatterjee, Tyler D. Baguley et al. · PLoS Biology · 2014 · 143 citations · Full text

Life Sciences, Neuroscience, Pharmacology +14

Neratinib protects pancreatic beta cells in diabetes

Amin Ardestani, Sijia Li, Karthika Annamalai et al. · Nature Communications · 2019 · 65 citations · Full text

Medicine, Endocrinology, Pharmacology +16

Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA

Katherine A. Rawls, P. Therese Lang, Jun Takeuchi et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 51 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +14

Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models

Jin Xu, Brigham J. Hartley, Pradeep Kurup et al. · Molecular Psychiatry · 2016 · 41 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Substrate-Based Fragment Identification for the Development of Selective, Nonpeptidic Inhibitors of Striatal-Enriched Protein Tyrosine Phosphatase

Tyler D. Baguley, Hai‐Chao Xu, Manavi Chatterjee et al. · Journal of Medicinal Chemistry · 2013 · 35 citations · Full text

Life Sciences, Medicinal Chemistry, Neuroscience +17