John M. Carethers

Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation.

Minoru Koi, Asad Umar, D P Chauhan et al. · PubMed · 1994 · 516 citations

Microm Mnng, Cytogenetics, Colon Tumor Cells +18

Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer

John M. Carethers, Edward J. Smith, Cynthia Behling et al. · Gastroenterology · 2004 · 460 citations · Full text

Microsatellite-unstable Colorectal Cancer, Medicine, Pathology +5

Mismatch repair proficiency and in vitro response to 5-fluorouracil

John M. Carethers, Dharam P. Chauhan, Daniel Fink et al. · Gastroenterology · 1999 · 422 citations · Full text

Experimental Therapeutic, Mismatch Repair Proficiency, Pharmacotherapy +3

Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint.

Mary T. Hawn, Asad Umar, John M. Carethers et al. · PubMed · 1995 · 363 citations

Cancer Research, Genome Instability, Cell Division +15

Frequent Inactivation of PTEN by Promoter Hypermethylation in Microsatellite Instability-High Sporadic Colorectal Cancers

Ajay Goel, Christian Arnold, Donna Niedzwiecki et al. · Cancer Research · 2004 · 302 citations