G. Gruia

Long-term survival of patients with unresectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil, leucovorin, oxaliplatin and surgery

Sylvie Giacchetti, M. Itzhaki, G. Gruia et al. · Annals of Oncology · 1999 · 607 citations

Medicine, Oncology, Surgery +16

Irinotecan Plus Gemcitabine Results in No Survival Advantage Compared With Gemcitabine Monotherapy in Patients With Locally Advanced or Metastatic Pancreatic Cancer Despite Increased Tumor Response Rate

Caio M. Rocha Lima, Mark R. Green, Robert Rotche et al. · Journal of Clinical Oncology · 2004 · 586 citations · Full text

Medicine, Oncology, Pharmacology +17

Irinotecan Plus Fluorouracil/Leucovorin for Metastatic Colorectal Cancer: A New Survival Standard

Leonard B. Saltz, Jean‐Yves Douillard, Nicoletta Pirotta et al. · The Oncologist · 2001 · 146 citations · Full text

Medicine, Oncology, Pharmacology +11

Phase I and Pharmacokinetic Study of Irinotecan Administered as a Low-Dose, Continuous Intravenous Infusion Over 14 Days in Patients With Malignant Solid Tumors

Virginie M.M. Herben, Jan H.M. Schellens, Martha Swart et al. · Journal of Clinical Oncology · 1999 · 58 citations

Medicine, Oncology, Pharmacology +17

Optimisation of irinotecan dose in the treatment of patients with metastatic colorectal cancer after 5-FU failure: results from a multinational, randomised phase II study

Eric Van Cutsem, Luc Dirix, J-L. van Laethem et al. · British Journal of Cancer · 2005 · 37 citations · Full text

Medicine, Oncology, Pharmacology +17