Debora Garcia Rodrigues

Improvement of paclitaxel therapeutic index by derivatization and association to a cholesterol-rich microemulsion: in vitro and in vivo studies

Debora Garcia Rodrigues, Durvanei Augusto Maria, Denise C. Fernandes et al. · Cancer Chemotherapy and Pharmacology · 2005 · 122 citations

Lipid Preparation, Nanomedicine, Pharmaceutical Science +12

Pharmacokinetics and tumor uptake of a derivatized form of paclitaxel associated to a cholesterol-rich nanoemulsion (LDE) in patients with gynecologic cancers

Maria Luiza Dias, Jesus Paula Carvalho, Debora Garcia Rodrigues et al. · Cancer Chemotherapy and Pharmacology · 2006 · 96 citations

Nanomedicine, Oncology, Polymer-drug Conjugate +8

Paclitaxel associated with cholesterol-rich nanoemulsions promotes atherosclerosis regression in the rabbit

Raul Cavalcante Maranhão, Elaine Rufo Tavares, A.F. Padoveze et al. · Atherosclerosis · 2008 · 91 citations

Inflammation, Nanomedicine, Atherosclerosis Regression +9

Metabolism of a cholesterol-rich microemulsion (LDE) in patients with multiple myeloma and a preliminary clinical study of LDE as a drug vehicle for the treatment of the disease

Vânia Hungria, Maria C. Latrilha, Debora Garcia Rodrigues et al. · Cancer Chemotherapy and Pharmacology · 2003 · 80 citations

Hematological Malignancy, Lipid Preparation, Medicine +9

Use of cholesterol-rich nanoparticles that bind to lipoprotein receptors as a vehicle to paclitaxel in the treatment of breast cancer: pharmacokinetics, tumor uptake and a pilot clinical study

Luís A. Pires, Roberto Hegg, Claudéte J. Valduga et al. · Cancer Chemotherapy and Pharmacology · 2008 · 80 citations · Full text

Nanoparticles, Nanomedicine, Engineering +9