Thierry Imbert

F14512, a Potent Antitumor Agent Targeting Topoisomerase II Vectored into Cancer Cells via the Polyamine Transport System

Jean‐Marc Barret, Anna Kruczynski, Stéphane Vispé et al. · Cancer Research · 2008 · 95 citations · Full text

Tumor Biology, Drug Targeting, Polyamine Transport System +13

F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action

Dominique Perrin, B van Hille, Jean‐Marc Barret et al. · Biochemical Pharmacology · 2000 · 87 citations

Medicinal Chemistry, Original Mechanism, Biochemistry +5

Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system

Anna Kruczynski, Isabelle Vandenberghe, Arnaud Pillon et al. · Investigational New Drugs · 2009 · 57 citations

Tumor Biology, Drug Target, Polymer-drug Conjugate +7

Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system

Yves Guminski, Martial Grousseaud, Sandrine Cugnasse et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 45 citations

Polyamine Transport System, Engineering, Bioimaging +5

Synthesis and Antitumor Activity of New Glycosides of Epipodophyllotoxin, Analogues of Etoposide, and NK 611

Laurent Daley, Yves Guminski, Pierre Demerseman et al. · Journal of Medicinal Chemistry · 1998 · 39 citations · Full text