Karl Yen

A CFTR Potentiator in Patients with Cystic Fibrosis and the <i>G551D</i> Mutation

Bonnie W. Ramsey, Jane C. Davies, Noel G. McElvaney et al. · New England Journal of Medicine · 2011 · 2.1K citations · Full text

Efficacy and Safety of Ivacaftor in Patients Aged 6 to 11 Years with Cystic Fibrosis with a <i>G551D</i> Mutation

Jane C. Davies, Claire Wainwright, Gerard J. Canny et al. · American Journal of Respiratory and Critical Care Medicine · 2013 · 499 citations · Full text

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the <i>F508del-CFTR</i> mutation

John P. Clancy, Steven M. Rowe, Frank J. Accurso et al. · Thorax · 2011 · 493 citations · Full text

Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies

Nicola A. Hanania, Michael Noonan, Jonathan Corren et al. · Thorax · 2015 · 374 citations · Full text

Ivacaftor in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation

Patrick A. Flume, Theodore G. Liou, Drucy Borowitz et al. · CHEST Journal · 2012 · 327 citations · Full text

Fibrosis, Mendelian Disorder, Genetic Disorder +9