Toru Beppu

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

Minoru Yoshida, Masako Kijima, Motomu Akita et al. · Journal of Biological Chemistry · 1990 · 1.9K citations · Full text

Histone Modifications, Molecular Biology, Epigenetics +20

Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase.

Masako Kijima, Minoru Yoshida, Kenji Sugita et al. · Journal of Biological Chemistry · 1993 · 510 citations · Full text

Histone Modifications, Antitumor Cyclic Tetrapeptide, Irreversible Inhibitor +21

Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression.

K. Nishi, Minoru Yoshida, Daisuke Fujiwara et al. · Journal of Biological Chemistry · 1994 · 455 citations · Full text

Molecular Regulation, Genetics, Molecular Biology +20

Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker

Tetsuya Nakatsura, Yoshihiro Yoshitake, Satoru Senju et al. · Biochemical and Biophysical Research Communications · 2003 · 428 citations

Oncology, Hepatology, Human Hepatocellular Carcinoma +10

Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma

Hasita Horlad, Yoshihiro Komohara, Hirohisa Okabe et al. · Cancer Science · 2010 · 269 citations · Full text

T-regulatory Cell, Immunology, Pathology +20