Toru Beppu

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

Minoru Yoshida, Masako Kijima, Motomu Akita et al. · Journal of Biological Chemistry · 1990 · 1.9K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase.

Masako Kijima, Minoru Yoshida, Kenji Sugita et al. · Journal of Biological Chemistry · 1993 · 512 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression.

K. Nishi, Minoru Yoshida, Daisuke Fujiwara et al. · Journal of Biological Chemistry · 1994 · 456 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker

Tetsuya Nakatsura, Yoshihiro Yoshitake, Satoru Senju et al. · Biochemical and Biophysical Research Communications · 2003 · 432 citations

Medicine, Cancer Biology, Oncology +14

Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma

Hasita Horlad, Yoshihiro Komohara, Toshiro Masuda et al. · Cancer Science · 2010 · 272 citations · Full text

Medicine, Oncology, Pathology +13