Stable Gene Transfer to Muscle Using Non-integrating Lentiviral Vectors

Luis Apolonia, Simon N. Waddington, Carolina Fernandes, +6

Molecular Therapy

Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin

Gerben Bouma, Wai Kwan Lam-Tse, Annet F. Wierenga‐Wolf, +2

Diabetes

Cell AdhesionImmunologyBlood CellPathologyInflammation +18

B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice

Mike Recher, Siobhan O. Burns, Miguel Á. de la Fuente, +32

Blood

Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

Almut Meyer‐Bahlburg, Shirly Becker-Herman, Stéphanie Humblet‐Baron, +6

Blood

Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells

Gerben Bouma, Siobhan O. Burns, Adrian J. Thrasher

Blood

Wasp-deficient Dendritic CellsLymphocyte DevelopmentT-regulatory CellImmunologyImmunologic Mechanism +14

Nonintegrating Lentivector Vaccines Stimulate Prolonged T-Cell and Antibody Responses and Are Effective in Tumor Therapy

Katarzyna Karwacz, Sayandip Mukherjee, Luis Apolonia, +5

Journal of Virology

Lentivector Vaccines StimulateHumoral ResponseImmunologyAntigen ProcessingCd4 T Cell Responses +22

The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell Function

Michael P. Blundell, Austen Worth, Gerben Bouma, +1

Disease Markers

ImmunologyPathologyCytoskeletonImmune Cell FunctionImmunotherapy +18

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1

Julien Record, Dessislava Malinova, Helen L. Zenner, +13

Blood

Functional Gap Junctions Accumulate at the Immunological Synapse and Contribute to T Cell Activation

Ariadna Mendoza‐Naranjo, Gerben Bouma, Cristián Pereda, +8

The Journal of Immunology

T-regulatory CellImmunologyImmunologic MechanismGap JunctionCytoskeleton +21

Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming

Gerben Bouma, Ariadna Mendoza‐Naranjo, Michael P. Blundell, +4

Blood