Mis-splicing yields circular RNA molecules.

Claude Cocquerelle, Bénédicte Mascrez, Dominique Hétuin, +1

The FASEB Journal

Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-γ and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway

Jizhong Liu, Abdelbasset Hamrouni, Dariusz Wołowiec, +5

Blood

In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors

Céline Berthon, Virginie Driss, Jizhong Liu, +5

Cancer Immunology Immunotherapy

NK cells that are activated by CXCL10 can kill dormant tumor cells that resist CTL-mediated lysis and can express B7-H1 that stimulates T cells

Aurore Saudemont, Nathalie Jouy, Dominique Hétuin, +1

Blood

RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage

A-L Nugues, Hassiba El Bouazzati, Dominique Hétuin, +6

Cell Death and Disease

γ‐Ray irradiation induces B7.1 expression in myeloid leukaemic cells

Rodolphe Vereecque, G Buffenoir, Ricardo R. González, +5

British Journal of Haematology

BCR-ABL mutants spread resistance to non-mutated cells through a paracrine mechanism

J Liu, Sami Joha, Thierry Idziorek, +5

Leukemia

Paracrine MechanismDrug Resistance AnalysisSignal TransductionBcr-abl MutantsMolecular Biology +4

Dormant Tumor Cells Develop Cross-Resistance to Apoptosis Induced by CTLs or Imatinib Mesylate via Methylation of Suppressor of Cytokine Signaling 1

Aurore Saudemont, Abdelbasset Hamrouni, Philippe Marchetti, +5

Cancer Research

Gene transfer of CD154 and IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia

Aurore Saudemont, G Buffenoir, Anne Denys, +6

Leukemia

Hematological MalignancyMedicineMixed-phenotype Acute LeukemiaHematologyImmunology +6

GILZ inhibits the mTORC2/AKT pathway in BCR-ABL+ cells

Sami Joha, A-L Nugues, Dominique Hétuin, +8

Oncogene