Concepedia

Author

Qiukan Chen

Children's Hospital of Philadelphia

Also Known As

Chen Qiukan, Qiukan Chen

21

Publications

635

Citations

12

H-Index

13

Concepts

All Affiliations

Children's Hospital of PhiladelphiaVirginia Commonwealth UniversityHarvard UniversityUniversity of Pennsylvania
QC

About

Qiukan Chen is an author at Children's Hospital of Philadelphia specializing in drug discovery, natural sciences, and medicinal chemistry.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

2

2

104

2

Natural Sciences

2

2

104

3

Biochemistry

2

2

104

4

Chemical Biology

1

1

51

5

Molecular Biology

1

1

51

Qiukan Chen

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13

Publications

623

Citations

12

H-Index

YearCitations

5‐hydroxymethyl‐2‐furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells<sup>†,‡</sup>

Osheiza Abdulmalik, Martin K. Safo, Qiukan Chen,

British Journal of Haematology

2005

240

Anti‐sickling effect of MX‐1520, a prodrug of vanillin: an <i>in vivo</i> study using rodents

Chaojie Zhang, Xiang Li, Lurong Lian,

British Journal of Haematology

2004

58

Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease

Guoyan Xu, Piyusha P. Pagare, Mohini S. Ghatge,

Molecular Pharmaceutics

2017

53

Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin

Osheiza Abdulmalik, Mohini S. Ghatge, Faik N. Musayev,

Acta Crystallographica Section D Biological Crystallography

2011

51

Correction of murine hemoglobinopathies by prenatal tolerance induction and postnatal nonmyeloablative allogeneic BM transplants

William H. Peranteau, Satoshi Hayashi, Osheiza Abdulmalik,

Blood

2015

48

Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease

Piyusha P. Pagare, Mohini S. Ghatge, Faik N. Musayev,

Bioorganic & Medicinal Chemistry

2018

36

A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells

Akito Nakagawa, Michele Ferrari, Grigorij Schleifer,

Molecular Pharmaceutics

2018

24

VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions

Osheiza Abdulmalik, Piyusha P. Pagare, Boshi Huang,

Scientific Reports

2020

23

1/T2 and Magnetic Susceptibility Measurements in a Gerbil Cardiac Iron Overload Model

Zhiyue Wang, Lurong Lian, Qiukan Chen,

Radiology

2005

22

Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation

Tanvi Deshpande, Piyusha P. Pagare, Mohini S. Ghatge,

Acta Crystallographica Section D Structural Biology

2018

22

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