Qiukan Chen

5‐hydroxymethyl‐2‐furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells^†,‡

Osheiza Abdulmalik, Martin K. Safo, Qiukan Chen et al. · British Journal of Haematology · 2005 · 243 citations · Full text

Medicine, Biochemistry, Pharmacology +12

Anti‐sickling effect of MX‐1520, a prodrug of vanillin: an <i>in vivo</i> study using rodents

Chaojie Zhang, Xiang Li, Lurong Lian et al. · British Journal of Haematology · 2004 · 58 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease

Guoyan Xu, Piyusha P. Pagare, Mohini S. Ghatge et al. · Molecular Pharmaceutics · 2017 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin

Osheiza Abdulmalik, Mohini S. Ghatge, Faik N. Musayev et al. · Acta Crystallographica Section D Biological Crystallography · 2011 · 52 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Correction of murine hemoglobinopathies by prenatal tolerance induction and postnatal nonmyeloablative allogeneic BM transplants

William H. Peranteau, Satoshi Hayashi, Osheiza Abdulmalik et al. · Blood · 2015 · 49 citations · Full text

Medicine, Hematology, Immunology +13