Small molecule‐driven SIRT3‐autophagy‐mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes

Tian Zhang, Zhu-Jun Fang, Ke‐Gang Linghu, +3

British Journal of Pharmacology

Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine

Wei Xiong, Wei Sang, Ke‐Gang Linghu, +6

International Journal of Nanomedicine

1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB

Ke‐Gang Linghu, Guoping Wu, Lingyun Fu, +6

Frontiers in Pharmacology

Siegesbeckia pubescens Makino inhibits Pam3CSK4-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-κB activation

Wei Sang, Zhangfeng Zhong, Ke‐Gang Linghu, +5

Chinese Medicine

Flaxseed extract induces apoptosis in human breast cancer MCF-7 cells

Tingyan Hu, Ke‐Gang Linghu, Siqi Huang, +7

Food and Chemical Toxicology

Breast OncologyOncologyMedicineApoptosisCell Death +5

Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation

Ke‐Gang Linghu, Shi Hang Xiong, Guan Ding Zhao, +8

Frontiers in Pharmacology

Ameliorating effects of 1,8-cineole on LPS-induced human umbilical vein endothelial cell injury by suppressing NF-κB signaling in vitro

Ke‐Gang Linghu, Dan Lin, Hong Yang, +5

European Journal of Pharmacology

InflammationEndothelial Cell PathobiologyCytokineAnti-inflammatoryAngiogenesis +10

Leocarpinolide B attenuates LPS-induced inflammation on RAW264.7 macrophages by mediating NF-κB and Nrf2 pathways

Ke‐Gang Linghu, Shuo Qiu, Guan Ding Zhao, +6

European Journal of Pharmacology

InflammationLeocarpinolide BAnti-inflammatoryNrf2 PathwaysImmune Cell Development +10

Essential oil from Fructus Alpinia zerumbet (fruit of Alpinia zerumbet (Pers.) Burtt.et Smith) protected against aortic endothelial cell injury and inflammation in vitro and in vivo

Yunpeng Ji, Ting-yu Shi, Yanyan Zhang, +6

Journal of Ethnopharmacology

InflammationPhysiologyPharmacologyEssential OilFructus Alpinia Zerumbet +7

Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations

Wei Xiong, Guan Ding Zhao, Xunqing Yin, +6

Carbohydrate Polymers

EngineeringSmart PolymerP-glycoprotein ModulationPolymer ScienceGlycobiology +6