mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1

Masahiro Morita, Julien Prudent, Kaustuv Basu, +14

Molecular Cell

Mitochondrial FunctionMitochondrial DynamicMedicineCell BiologyCell Signaling +1

PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs

Sylvia Andrzejewski, Eva Klimčáková, Radia Marie Johnson, +9

Cell Metabolism

Breast OncologyMedicineMetabolic DrugsBreast CancerMetabolic Remodeling +6

PGC-1α supports glutamine metabolism in breast cancer

Shawn McGuirk, Simon‐Pierre Gravel, Geneviève Deblois, +9

Cancer & Metabolism

Estrogen-related receptors are targetable ROS sensors

Mathieu Vernier, Catherine R. Dufour, Shawn McGuirk, +8

Genes & Development

Breast OncologyCancer BiologyTumor BiologyOxidative StressOvarian Cancer +20

Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1α

Anne‐Sophie Arnold, Jonathan F. Gill, Martine Christe, +5

Nature Communications

MechanobiologyMuscle PhysiologyNeuromuscular JunctionMolecular PhysiologyDevelopmental Biology +12

Androgen-Dependent Repression of ERRγ Reprograms Metabolism in Prostate Cancer

Étienne Audet‐Walsh, Tracey Yee, Shawn McGuirk, +4

Cancer Research

PGC-1α Promotes the Growth of ErbB2/Neu–Induced Mammary Tumors by Regulating Nutrient Supply

Eva Klimčáková, Valérie Chénard, Shawn McGuirk, +4

Cancer Research

Metabolic RemodelingMitochondrial FunctionsCancer BiologyMammary Gland DevelopmentTumor Biology +19

Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4

Mathieu Vernier, Shawn McGuirk, Catherine R. Dufour, +4

Oncogene

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

Shawn McGuirk, Yannick Audet-Delage, Matthew G. Annis, +12

eLife

Peroxisome proliferator‐activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging

Jonathan F. Gill, Julien Delezie, Gesa Santos, +6

Aging Cell