Seyha Kem

Nicotinamide Offers Multiple Protective Mechanisms in Stroke as a Precursor for NAD<sup>+</sup>, as a PARP Inhibitor and by Partial Restoration of Mitochondrial Function

Lori K. Klaidman, María Paz Morales, Seyha Kem et al. · Pharmacology · 2003 · 119 citations

Parp Inhibitor, Mitochondrial Nad-linked Respiration, Brain Mitochondrial Function +25

Nicotinamide therapy protects against both necrosis and apoptosis in a stroke model

Jun Yang, Lori K. Klaidman, Mei Ling Chang et al. · Pharmacology Biochemistry and Behavior · 2002 · 90 citations

Cell Death, Cerebrovascular Disease, Nicotinamide Therapy Protects +18

Nicotinamide and ketamine reduce infarct volume and DNA fragmentation in rats after brain ischemia and reperfusion

Mei Ling Chang, Jun Yang, Seyha Kem et al. · Neuroscience Letters · 2002 · 48 citations

Dna Fragmentation, Cerebrovascular Disease, Pharmacotherapy +16