Concepedia

Author

Jaclyn N. Highland

University of Maryland, BaltimoreORCID

Also Known As

Highland, Jaclyn N., Jaclyn Highland, Jaclyn N Highland, Jaclyn N. Highland

17

Publications

1.9K

Citations

10

H-Index

10

Concepts

All Affiliations

University of Maryland, BaltimoreNational Institute on AgingNational Institutes of HealthVA Maryland Health Care SystemNational Institute of Mental Health
JN

About

Jaclyn N. Highland is an author at University of Maryland, Baltimore specializing in medicine, neuropharmacology, and social sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

2

2

182

2

Social Sciences

2

2

182

3

Neuroscience

2

2

182

4

Pharmacology

1

1

55

5

Behavioral Neuroscience

1

1

127

Jaclyn N. Highland

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8

Publications

627

Citations

8

H-Index

YearCitations

( <i>2R,6R</i> )-hydroxynorketamine exerts mGlu <sub>2</sub> receptor-dependent antidepressant actions

Panos Zanos, Jaclyn N. Highland, Brent W. Stewart,

Proceedings of the National Academy of Sciences

2019

147

Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor

Polymnia Georgiou, Panos Zanos, Ta-Chung M. Mou,

Nature Neuroscience

2022

127

A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice

Panos Zanos, Mackenzie E. Nelson, Jaclyn N. Highland,

eNeuro

2017

107

(<i>R</i>)‐Ketamine exerts antidepressant actions partly via conversion to (<i>2R,6R</i>)‐hydroxynorketamine, while causing adverse effects at sub‐anaesthetic doses

Panos Zanos, Jaclyn N. Highland, Xin Liu,

British Journal of Pharmacology

2019

81

Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of (<i>2R,6R</i>)-hydroxynorketamine

Jaclyn N. Highland, Patrick J. Morris, Panos Zanos,

Journal of Psychopharmacology

2018

58

Group II metabotropic glutamate receptor blockade promotes stress resilience in mice

Jaclyn N. Highland, Panos Zanos, Polymnia Georgiou,

Neuropsychopharmacology

2019

55

Sex-dependent metabolism of ketamine and (<i>2R,6R</i>)-hydroxynorketamine in mice and humans

Jaclyn N. Highland, Cristan Farmer, Panos Zanos,

Journal of Psychopharmacology

2021

29

Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (2<i>,</i>6)- and (5<i>R</i>)-Methyl-(2<i>R,</i>6<i>R</i>)-hydroxynorketamines

Jaclyn N. Highland, Patrick J. Morris, Kylie M. Konrath,

ACS Chemical Neuroscience

2022

23

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