Single Mammalian Cells Compensate for Differences in Cellular Volume and DNA Copy Number through Independent Global Transcriptional Mechanisms

Olivia Padovan‐Merhar, Gautham Nair, Andrew G. Biaesch, +7

Molecular Cell

Transcriptional RegulationCell LineageHuman CellCellular VolumeSingle Cell Sequencing +9

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Melissa B. Pappalardi, Kathryn Keenan, Mark Cockerill, +59

Nature Cancer

Hematological MalignancyMedicineAcute Myeloid LeukemiaMixed-phenotype Acute LeukemiaPharmacology +7

Global Analysis of the RNA-Protein Interaction and RNA Secondary Structure Landscapes of the Arabidopsis Nucleus

Sager J. Gosai, Shawn W. Foley, Dongxue Wang, +7

Molecular Cell

BiologyPlant Molecular BiologyNatural SciencesGeneticsRna Structure Prediction +8

Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

Ihab Younis, Kimberly A. Dittmar, Wei Wang, +6

eLife

Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein of the testis carcinoma and other cancers: Results of a Phase <scp>I</scp>/<scp>II</scp> open‐label, dose escalation study

Sophie Cousin, Jean‐Yves Blay, Irene García, +27

International Journal of Cancer

Cancer ManagementPharmacotherapyTestis CarcinomaMolecular PharmacologyOncology +15

A Global View of RNA-Protein Interactions Identifies Post-transcriptional Regulators of Root Hair Cell Fate

Shawn W. Foley, Sager J. Gosai, Dongxue Wang, +10

Developmental Cell

Transcriptional RegulationGlobal ViewDevelopmental BiologyGeneticsRna Biology +7

MEK inhibitors overcome resistance to BET inhibition across a number of solid and hematologic cancers

Anastasia Wyce, Jeanne J. Matteo, Shawn W. Foley, +15

Oncogenesis

A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies

Mark A. Dawson, Gautam Borthakur, Brian J.P. Huntly, +28

Clinical Cancer Research

The LIN28B–IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestine

Priya Chatterji, Kathryn E. Hamilton, Shun Liang, +15

Genes & Development

Protein Interaction Profile Sequencing (PIP‐seq)

Shawn W. Foley, Brian D. Gregory

Current Protocols in Molecular Biology