George A. Moniz

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling

Sharon McGonigle, Zhihong Chen, Jiayi Wu et al. · Oncotarget · 2015 · 87 citations · Full text

Medicine, Molecular Biology, Oncology +15

Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (<i>S</i>)-2-((1<i>S</i>,2<i>S</i>,4<i>R</i>)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5<i>H</i>)-one (AMG 221)

Murielle M. Véniant, Clarence Hale, Randall W. Hungate et al. · Journal of Medicinal Chemistry · 2010 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Development of a Rhodium Carbenoid-Initiated Claisen Rearrangement for the Enantioselective Synthesis of α-Hydroxy Carbonyl Compounds

John L. Wood, George A. Moniz, Derek A. Pflum et al. · Journal of the American Chemical Society · 1999 · 74 citations

Natural Sciences, Chemistry, Catalysis +7

An Aldol-Based Synthesis of (+)-Peloruside A, A Potent Microtubule Stabilizing Agent

David A. Evans, Dennie S. Welch, Alexander W. H. Speed et al. · Journal of the American Chemical Society · 2009 · 67 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +16

Catalyst-Based Control of [2,3]- and [3,3]-Rearrangement in α-Diazoketone-Derived Propargyloxy Enols

George A. Moniz, John L. Wood · Journal of the American Chemical Society · 2001 · 62 citations

Natural Sciences, Chemistry, Catalysis +6