Nathalie Lefort

Striatal progenitors derived from human ES cells mature into DARPP32 neurons<i>in vitro</i>and in quinolinic acid-lesioned rats

Laëtitia Aubry, Aurore Bugi, Nathalie Lefort et al. · Proceedings of the National Academy of Sciences · 2008 · 290 citations · Full text

Fetal Cells, Substitutive Cell Therapy, Cellular Neurobiology +25

Involvement of Mitochondrial Complex II Defects in Neuronal Death Produced by N-Terminus Fragment of Mutated Huntingtin

Alexandra Benchoua, Yaël Trioulier, Diana Zala et al. · Molecular Biology of the Cell · 2006 · 241 citations · Full text

Mitophagy, Mitochondrial Dysfunction, Cell Death +16

Human embryonic stem cells reveal recurrent genomic instability at 20q11.21

Nathalie Lefort, Maxime Feyeux, Cécile Bas et al. · Nature Biotechnology · 2008 · 227 citations

Genome Instability, Developmental Biology, Medicine +6

Early transcriptional changes linked to naturally occurring Huntington's disease mutations in neural derivatives of human embryonic stem cells

Maxime Feyeux, Fany Bourgois-Rocha, Amanda Redfern et al. · Human Molecular Genetics · 2012 · 71 citations · Full text

Genetics, Genomic Mechanism, Gene Characterization +20

MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia

Ekin Ucuncu, Karthyayani Rajamani, Miranda Wilson et al. · Nature Communications · 2020 · 60 citations · Full text